Sub-Inhibitory Concentrations of Mupirocin Strongly Inhibit Alpha-Toxin Production in High-Level Mupirocin-Resistant MRSA by Down-Regulating agr, saeRS, and sarA

Mupirocin, a topical antibiotic, has been utilized for decades to treat Staphylococcus aureus skin infections, as well as to decolonize patients at risk of methicillin-resistant S. aureus (MRSA) infection. The aims of this study were to investigate the expression of α-toxin (encoded by the hla gene)...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Jin, Ye, Li, Meilan, Shang, Yongpeng, Liu, Li, Shen, Xiaofei, Lv, Zhihui, Hao, Zhihao, Duan, Jingjing, Wu, Yang, Chen, Chun, Pan, Jingye, Yu, Fangyou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962727/
https://ncbi.nlm.nih.gov/pubmed/29867891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00993
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