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Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond
Basal cell carcinoma (BCC) of the skin is driven by aberrant hedgehog signaling. Thus blocking this signaling pathway by small molecules such as vismodegib inhibits tumor growth. Primary cilium in the epidermal cells plays an integral role in the processing of hedgehog signaling-related proteins. Re...
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| Publicado no: | Mol Carcinog |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5962346/ https://ncbi.nlm.nih.gov/pubmed/28574612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22690 |
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