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Exploring Landscape of Drug-Target-Pathway-Side Effect Associations

Side effects are the second and the fourth leading causes of drug attrition and death in the US. Thus, accurate prediction of side effects and understanding their mechanism of action will significantly impact drug discovery and clinical practice. Here, we show REMAP, a neighborhood-regularized weigh...

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Pubblicato in:AMIA Jt Summits Transl Sci Proc
Autori principali: Lim, Hansaim, Poleksic, Aleksandar, Xie, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Informatics Association 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961812/
https://ncbi.nlm.nih.gov/pubmed/29888057
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