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Foldamer Tertiary Structure through Sequence-Guided Protein Backbone Alteration

The prospect of recreating the complex structural hierarchy of protein folding in synthetic oligomers with backbones that are artificial in covalent structure (“foldamers”) has long fascinated chemists. Foldamers offer complex functions from biostable scaffolds and have found widespread applications...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acc Chem Res
Hauptverfasser: George, Kelly L., Horne, W. Seth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953838/
https://ncbi.nlm.nih.gov/pubmed/29672021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.8b00048
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