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Methamphetamine Induces TET1- and TET3-Dependent DNA Hydroxymethylation of Crh and Avp Genes in the Rat Nucleus Accumbens

Methamphetamine (METH) addiction is a biopsychosocial disorder that is accompanied by multiple relapses even after prolonged abstinence, suggesting the possibilities of long-lasting maladaptive epigenetic changes in the brain. Here, we show that METH administration produced time-dependent increases...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Jayanthi, Subramaniam, Gonzalez, Betina, McCoy, Michael T., Ladenheim, Bruce, Bisagno, Veronica, Cadet, Jean Lud
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948251/
https://ncbi.nlm.nih.gov/pubmed/28842817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0750-9
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