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In vivo and in vitro oncogenic effects of HIF2A mutations in pheochromocytomas and paragangliomas
Pheochromocytomas and paragangliomas are highly vascular tumors of the autonomic nervous system. Germline mutations, including those in hypoxia-related genes, occur in one-third of the cases, but somatic mutations are infrequent in these tumors. Using exome sequencing of 6 paired constitutive and tu...
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| 出版年: | Endocr Relat Cancer |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944295/ https://ncbi.nlm.nih.gov/pubmed/23533246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0101 |
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