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GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level

Radioresistance remains a major clinical challenge in cervical cancer therapy. However, the mechanism for the development of radioresistance in cervical cancer is unclear. Herein, we determined that growth arrest and DNA-damage-inducible protein 45α (GADD45α) is decreased in radioresistant cervical...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Li, Qing, Wei, Xi, Zhou, Zhi-Wei, Wang, Shu-Nan, Jin, Hua, Chen, Kui-Jun, Luo, Jia, Westover, Kenneth D., Wang, Jian-Min, Wang, Dong, Xu, Cheng-Xiong, Shan, Jin-Lu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943293/
https://ncbi.nlm.nih.gov/pubmed/29743554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0452-x
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