Genome-wide identification and characterization of Notch transcription complex-binding sequence paired sites in leukemia cells

Notch transcription complexes (NTCs) drive target gene expression by binding to two distinct types of genomic response elements, NTC monomer-binding sites and sequence-paired sites (SPSs) that bind NTC dimers. SPSs are conserved and are linked to the Notch-responsiveness of a few genes, but their ov...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Severson, Eric, Arnett, Kelly L., Wang, Hongfang, Zang, Chongzhi, Taing, Len, Liu, Hudan, Pear, Warren S., Liu, X. Shirley, Blacklow, Stephen C., Aster, Jon C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931361/
https://ncbi.nlm.nih.gov/pubmed/28465412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aag1598
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