Infrequent Mutation of the hBUB1 and hBUBR1 Genes in Human Lung Cancer

Mitotic checkpoint defects of the cell cycle have been implicated in the development of human cancers. Since hBUB1 and hBUBR1, whose products function in the spindle checkpoint pathway, have been shown to be mutated in a subset of colon cancers with chromosomal instability, we investigated the contr...

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Publicat a:Jpn J Cancer Res
Autors principals: Sato, Mitsuo, Sekido, Yoshitaka, Horio, Yoshitsugu, Takahashi, Masahide, Saito, Hidehiko, Minna, John D., Shimokata, Kaoru, Hasegawa, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926378/
https://ncbi.nlm.nih.gov/pubmed/10835495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00974.x
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