Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

Major advances in donor identification, antigen probe design, and experimental methods to clone pathogen-specific antibodies have led to an exponential growth in the number of newly characterized broadly neutralizing antibodies (bnAbs) that recognize the HIV-1 envelope glycoprotein. Characterization...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Cheng, Hao D., Grimm, Sebastian K., Gilman, Morgan S.A., Gwom, Luc Christian, Sok, Devin, Sundling, Christopher, Donofrio, Gina, Hedestam, Gunilla B. Karlsson, Bonsignori, Mattia, Haynes, Barton F., Lahey, Timothy P., Maro, Isaac, von Reyn, C. Fordham, Gorny, Miroslaw K., Zolla-Pazner, Susan, Walker, Bruce D., Alter, Galit, Burton, Dennis R., Robb, Merlin L., Krebs, Shelly J., Seaman, Michael S., Bailey-Kellogg, Chris, Ackerman, Margaret E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Technical Advance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922287/
https://ncbi.nlm.nih.gov/pubmed/29515029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97018
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