Restoration of the Cellular Senescence Program and Repression of Telomerase by Human Chromosome 3

Telomeres, at the end of chromosomes, shorten with each cell division, resulting in cellular senescence. Tumor cells, unlike normal somatic cells, express a telomerase that maintains the telomere length. Deletion of a gene(s) on chromosome 3 is common in human renal cell carcinoma (RCC) and reintrod...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Ohmura, Hiroshi, Tahara, Hidetoshi, Suzuki, Mikio, Ide, Toshinori, Shimizu, Motoyuki, Yoshida, Mitsuaki A., Tahara, Eiichi, Shay, Jerry W., Barrett, J. Carl, Oshimura, Mitsuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1995
Témata:
Rapid Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920601/
https://ncbi.nlm.nih.gov/pubmed/7493906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb02998.x
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