Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway

Methamphetamine (METH) is a drug with a high addictive potential that is widely abused across the world. Although it is known that METH dysregulates both dopamine transmission and dopamine reuptake, the specific mechanism of action remains obscure. One promising target of METH is the sigma receptor,...

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Publicado en:Neuropsychopharmacology
Autores principales: Hedges, David M, Obray, J Daniel, Yorgason, Jordan T, Jang, Eun Young, Weerasekara, Vajira K, Uys, Joachim D, Bellinger, Frederick P, Steffensen, Scott C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916361/
https://ncbi.nlm.nih.gov/pubmed/29185481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.291
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