THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders

There is a strong association between cannabis use and schizophrenia but the underlying cellular links are poorly understood. Neurons derived from human-induced pluripotent stem cells (hiPSCs) offer a platform for investigating both baseline and dynamic changes in human neural cells. Here, we expose...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Guennewig, Boris, Bitar, Maina, Obiorah, Ifeanyi, Hanks, James, O’Brien, Elizabeth A., Kaczorowski, Dominik C., Hurd, Yasmin L., Roussos, Panos, Brennand, Kristen J., Barry, Guy
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915454/
https://ncbi.nlm.nih.gov/pubmed/29691375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0137-3
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