Lateral habenula perturbation reduces default-mode network connectivity in a rat model of depression

Hyperconnectivity of the default-mode network (DMN) is one of the most widely replicated neuroimaging findings in major depressive disorder (MDD). Further, there is growing evidence for a central role of the lateral habenula (LHb) in the pathophysiology of MDD. There is preliminary neuroimaging evid...

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Udgivet i:Transl Psychiatry
Main Authors: Clemm von Hohenberg, Christian, Weber-Fahr, Wolfgang, Lebhardt, Philipp, Ravi, Namasivayam, Braun, Urs, Gass, Natalia, Becker, Robert, Sack, Markus, Cosa Linan, Alejandro, Gerchen, Martin Fungisai, Reinwald, Jonathan Rochus, Oettl, Lars-Lennart, Meyer-Lindenberg, Andreas, Vollmayr, Barbara, Kelsch, Wolfgang, Sartorius, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913319/
https://ncbi.nlm.nih.gov/pubmed/29581421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0121-y
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