The Role of PIEZO2 in Human Mechanosensation

BACKGROUND: The senses of touch and proprioception evoke a range of perceptions and rely on the ability to detect and transduce mechanical force. The molecular and neural mechanisms underlying these sensory functions remain poorly defined. The stretch-gated ion channel PIEZO2 has been shown to be es...

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Vydáno v:N Engl J Med
Hlavní autoři: Chesler, Alexander T., Szczot, Marcin, Bharucha-Goebel, Diana, Čeko, Marta, Donkervoort, Sandra, Laubacher, Claire, Hayes, Leslie H., Alter, Katharine, Zampieri, Cristiane, Stanley, Christopher, Innes, A. Micheil, Mah, Jean K., Grosmann, Carla M., Bradley, Nathaniel, Nguyen, David, Foley, A. Reghan, Le Pichon, Claire E., Bönnemann, Carsten G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911918/
https://ncbi.nlm.nih.gov/pubmed/27653382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1602812
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