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Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis

Peritoneal metastasis is a major cause of morbidity and mortality in ovarian cancer. While intraperitoneal chemotherapy and radiotherapy have shown favorable clinical results, both are limited by their non-targeted nature. We aimed to develop a biologically targeted nanoparticle therapeutic for the...

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Publicado en:Biomaterials
Autores principales: Werner, Michael E., Karve, Shrirang, Sukumar, Rohit, Cummings, Natalie D., Copp, Jonathan A., Chen, Ronald C., Zhang, Tian, Wang, Andrew Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911366/
https://ncbi.nlm.nih.gov/pubmed/21843904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.07.067
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