Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages

OBJECTIVES: We examined the in vitro pharmacodynamics and cellular accumulation of the standard anti-leishmanial drugs amphotericin B and miltefosine in intracellular Leishmania donovani amastigote–macrophage drug assays. METHODS: Primary mouse macrophages were infected with L. donovani amastigotes....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Antimicrob Chemother
Egile Nagusiak: Voak, Andrew A, Standing, Joseph F, Sepúlveda, Nuno, Harris, Andy, Croft, Simon L, Seifert, Karin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909632/
https://ncbi.nlm.nih.gov/pubmed/29506127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky014
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