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Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages

OBJECTIVES: We examined the in vitro pharmacodynamics and cellular accumulation of the standard anti-leishmanial drugs amphotericin B and miltefosine in intracellular Leishmania donovani amastigote–macrophage drug assays. METHODS: Primary mouse macrophages were infected with L. donovani amastigotes....

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Podrobná bibliografie
Vydáno v:J Antimicrob Chemother
Hlavní autoři: Voak, Andrew A, Standing, Joseph F, Sepúlveda, Nuno, Harris, Andy, Croft, Simon L, Seifert, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909632/
https://ncbi.nlm.nih.gov/pubmed/29506127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky014
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