Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2–Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow

Ex vivo regional gene therapy strategies using animal mesenchymal stem cells genetically modified to overexpress osteoinductive growth factors have been successfully used in a variety of animal models to induce both heterotopic and orthotopic bone formation. However, in order to adapt regional gene...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Bougioukli, Sofia, Sugiyama, Osamu, Pannell, William, Ortega, Brandon, Tan, Matthew H., Tang, Amy H., Yoho, Robert, Oakes, Daniel A., Lieberman, Jay R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909082/
https://ncbi.nlm.nih.gov/pubmed/29212377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.097
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