Glycine Protects H9C2 Cardiomyocytes from High Glucose- and Hypoxia/Reoxygenation-Induced Injury via Inhibiting PKCβ2 Activation and Improving Mitochondrial Quality

BACKGROUND: Patients with diabetes are more vulnerable to myocardial ischemia reperfusion injury (IRI), which is involved in PKCβ2 activation and mitochondrial dysfunction. Glycine has been documented as a cytoprotective agent to attenuate diabetes-related abnormalities and reduce myocardial IRI, bu...

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Publicado en:J Diabetes Res
Autores principales: Zhang, Yuan, Su, Wating, Zhang, Qiongxia, Xu, Jinjin, Liu, Huimin, Luo, Jun, Zhan, Liying, Xia, Zhongyuan, Lei, Shaoqing
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904807/
https://ncbi.nlm.nih.gov/pubmed/29850613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9502895
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