Soluble syntaxin 3 functions as a transcriptional regulator

Syntaxins are a conserved family of SNARE proteins and contain C-terminal transmembrane anchors required for their membrane fusion activity. Here we show that Stx3 (syntaxin 3) unexpectedly also functions as a nuclear regulator of gene expression. We found that alternative splicing creates a soluble...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Giovannone, Adrian J., Winterstein, Christine, Bhattaram, Pallavi, Reales, Elena, Low, Seng Hui, Baggs, Julie E., Xu, Mimi, Lalli, Matthew A., Hogenesch, John B., Weimbs, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900775/
https://ncbi.nlm.nih.gov/pubmed/29475951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000874
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