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Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes

Clinical studies have suggested that myocardial iron is a risk factor for left ventricular remodeling in patients after myocardial infarction. Ferroptosis has recently been reported as a mechanism of iron-dependent nonapoptotic cell death. However, ferroptosis in the heart is not well understood. Me...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Baba, Yuichi, Higa, Jason K., Shimada, Briana K., Horiuchi, Kate M., Suhara, Tomohiro, Kobayashi, Motoi, Woo, Jonathan D., Aoyagi, Hiroko, Marh, Karra S., Kitaoka, Hiroaki, Matsui, Takashi
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899260/
https://ncbi.nlm.nih.gov/pubmed/29127238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00452.2017
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