Macromolecular Crowding May Significantly Affect the Performance of an MRI Contrast Agent: A (1)H NMR Spectroscopy, Microimaging, and Fast‐Field‐Cycling NMR Relaxometry Study

Contrast enhancement agents are often employed in magnetic resonance imaging (MRI) for clinical diagnosis and biomedical research. However, the current theory on MRI contrast generation does not consider the ubiquitous presence of macromolecular crowders in biological systems, which poses the risk o...

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Pubblicato in:ChemistryOpen
Autori principali: Cheng, Ren‐Hao, Chen, Jie‐Min, Chen, Yu‐Wen, Cai, Honghao, Cui, Xiaohong, Hwang, Dennis W., Chen, Zhong, Ding, Shangwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891664/
https://ncbi.nlm.nih.gov/pubmed/29657915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201700192
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