Markers of gut dysfunction do not explain low rifampicin bioavailability in HIV-associated TB

Background: Rifampicin is the key drug responsible for sterilizing activities in the first-line TB treatment regimen. Damage to the gut during acute and chronic HIV infection may inhibit drug absorptive capacity. We sought to test the hypothesis that markers of intestinal damage, bacterial transloca...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Vinnard, Christopher, Ravimohan, Shruthi, Tamuhla, Neo, Pasipanodya, Jotam, Srivastava, Shashikant, Modongo, Chawangwa, Zetola, Nicola M., Weissman, Drew, Gumbo, Tawanda, Bisson, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890696/
https://ncbi.nlm.nih.gov/pubmed/28472448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx111
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