6′-O-Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation

6′-O-galloylpaeoniflorin (GPF), a galloylated derivative of paeoniflorin isolated from peony root, has been proven to possess antioxidant potential. In this present study, we revealed that GPF treatment exerted significant neuroprotection of PC12 cells following OGD, as evidenced by a reduction of o...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Wen, Zhongmei, Hou, Weichen, Wu, Wei, Zhao, Yang, Dong, Xuechao, Bai, Xiaoxue, Peng, Liping, Song, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889897/
https://ncbi.nlm.nih.gov/pubmed/29765506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8678267
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