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Bile Acids Increase Doxorubicin Sensitivity in ABCC1-expressing Tumour Cells

Tumour cells possess or acquire various mechanisms to circumvent the cytotoxic effects of chemotherapy drugs. One such mechanism involves the overexpression of ABC transporters that facilitate the extrusion of a variety of structurally distinct chemotherapy drugs from the cytoplasm into the extracel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chewchuk, Simon, Boorman, Tyler, Edwardson, Derek, Parissenti, Amadeo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882947/
https://ncbi.nlm.nih.gov/pubmed/29615646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23496-y
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