Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses

To elucidate the adaptive strategies of influenza A viruses (IAVs) to human, we proposed a computational approach to identify human-adaptive mutations in seasonal IAVs, which have not been analyzed comprehensively. We compared representative PB2 sequences of 1425 avian IAVs and 2176 human IAVs and i...

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Bibliographic Details
Published in:Emerg Microbes Infect
Main Authors: Wen, Lei, Chu, Hin, Wong, Bosco Ho-Yin, Wang, Dong, Li, Cun, Zhao, Xiaoyu, Chiu, Man-Chun, Yuan, Shuofeng, Fan, Yanhui, Chen, Honglin, Zhou, Jie, Yuen, Kwok-Yung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874250/
https://ncbi.nlm.nih.gov/pubmed/29593225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0050-0
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