Nicotinic Modulation of Descending Pain Control Circuitry

Along with the well-known rewarding effects, activation of nicotinic acetylcholine receptors (nAChRs) can also relieve pain, and some nicotinic agonists have analgesic efficacy similar to opioids. A major target of analgesic drugs is the descending pain modulatory pathway, including the ventrolatera...

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Bibliographic Details
Published in:Pain
Main Authors: Umana, Iboro C., Daniele, Claire A., Miller, Brooke A., Abburi, Chandrika, Gallagher, Keith, Brown, Meghan A., Mason, Peggy, McGehee, Daniel S.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873975/
https://ncbi.nlm.nih.gov/pubmed/28817416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000993
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