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Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death

The integrity of the avascular nucleus pulposus (NP) phenotype plays a crucial role in the maintenance of intervertebral disc health. While advances have been made to define the molecular phenotype of healthy NP cells, the functional relevance of several of these markers remains unknown. In this stu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Silagi, Elizabeth S., Batista, Philip, Shapiro, Irving M., Risbud, Makarand V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861082/
https://ncbi.nlm.nih.gov/pubmed/29559661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23196-7
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