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Physiological and pathophysiological bone turnover — role of the immune system

Osteoporosis develops when the rate of osteoclastic bone breakdown (resorption) exceeds that of osteoblastic bone formation, which leads to loss of BMD and deterioration of bone structure and strength. Osteoporosis increases the risk of fragility fractures, a cause of substantial morbidity and morta...

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Bibliographic Details
Published in:Nat Rev Endocrinol
Main Authors: Weitzmann, M. Neale, Ofotokun, Ighovwerha
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857945/
https://ncbi.nlm.nih.gov/pubmed/27312863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2016.91
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