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Interleukin‐17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis

Tuberculosis (TB) is characterized by extensive pulmonary matrix breakdown. Interleukin‐17 (IL‐17) is key in host defence in TB but its role in TB‐driven tissue damage is unknown. We investigated the hypothesis that respiratory stromal cell matrix metalloproteinase (MMP) production in TB is regulate...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Singh, Shivani, Maniakis‐Grivas, George, Singh, Utpal K, Asher, Radha M, Mauri, Francesco, Elkington, Paul T, Friedland, Jon S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838784/
https://ncbi.nlm.nih.gov/pubmed/29210073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5013
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