The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways

Host colonization by Gram-negative pathogens often involves delivery of bacterial proteins called “effectors” into the host cell. The pneumonia-causing pathogen Legionella pneumophila delivers more than 330 effectors into the host cell via its type IVB Dot/Icm secretion system. The collective functi...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Quaile, Andrew T., Stogios, Peter J., Egorova, Olga, Evdokimova, Elena, Valleau, Dylan, Nocek, Boguslaw, Kompella, Purnima S., Peisajovich, Sergio, Yakunin, Alexander F., Ensminger, Alexander W., Savchenko, Alexei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836138/
https://ncbi.nlm.nih.gov/pubmed/29301934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812727
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