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Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca(2+)-signaling
Endoplasmic reticulum (ER) stress results from protein unfolding/misfolding during cellular maturation, which requires a coordinated action of several chaperones and enzymes and Ca(2+) signalling. ER-stress possibly has a positive effect on survival of pancreatic cancer cell. Therefore, detailed ins...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834441/ https://ncbi.nlm.nih.gov/pubmed/29500369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22143-w |
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