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Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization

The objective of this study is to design a graphene‐based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene delivery system is developed using polyethylenimine (PEI) functionalized graphene oxide (GO) complex loaded with miR‐7b overexpression plasmid. GO‐...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Dou, Ce, Ding, Ning, Luo, Fei, Hou, Tianyong, Cao, Zhen, Bai, Yun, Liu, Chuan, Xu, Jianzhong, Dong, Shiwu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826985/
https://ncbi.nlm.nih.gov/pubmed/29619305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201700578
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