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Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization

The objective of this study is to design a graphene‐based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene delivery system is developed using polyethylenimine (PEI) functionalized graphene oxide (GO) complex loaded with miR‐7b overexpression plasmid. GO‐...

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Dettagli Bibliografici
Pubblicato in:Adv Sci (Weinh)
Autori principali: Dou, Ce, Ding, Ning, Luo, Fei, Hou, Tianyong, Cao, Zhen, Bai, Yun, Liu, Chuan, Xu, Jianzhong, Dong, Shiwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826985/
https://ncbi.nlm.nih.gov/pubmed/29619305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201700578
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