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Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance

Notch signaling is required for the development and physiology of nearly every tissue in metazoans. Much of Notch signaling is mediated by transcriptional regulation of downstream target genes, but Notch controls axon patterning in Drosophila by local modulation of Abl tyrosine kinase signaling, via...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Kannan, Ramakrishnan, Cox, Eric, Wang, Lei, Kuzina, Irina, Gu, Qun, Giniger, Edward
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825841/
https://ncbi.nlm.nih.gov/pubmed/29343637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.151548
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