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The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway

Microbial or endogenous molecular patterns as well as pathogen functional features can activate innate immune systems. Whereas detection of infection by pattern recognition receptors has been investigated in details, sensing of virulence factors activities remains less characterized. In Drosophila,...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Issa, Najwa, Guillaumot, Nina, Lauret, Emilie, Matt, Nicolas, Schaeffer-Reiss, Christine, Van Dorsselaer, Alain, Reichhart, Jean-Marc, Veillard, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823974/
https://ncbi.nlm.nih.gov/pubmed/29452635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.029
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