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HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to splenomegaly and ultimately immune suppression. Inflam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hammami, Akil, Abidin, Belma Melda, Heinonen, Krista M., Stäger, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823892/
https://ncbi.nlm.nih.gov/pubmed/29472618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21891-z
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