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Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations

Tumour angiogenesis is an important hallmark of cancer and the study of its metabolic adaptations, downstream to any cellular change, can reveal attractive targets for inhibiting cancer growth. In the tumour microenvironment, endothelial cells (ECs) interact with heterogeneous tumour cell types that...

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Bibliographic Details
Published in:PLoS One
Main Authors: Jayaraman, Anusha, Kumar, Praveen, Marin, Silvia, de Atauri, Pedro, Mateo, Francesca, M. Thomson, Timothy, J. Centelles, Josep, F. Graham, Stewart, Cascante, Marta
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821452/
https://ncbi.nlm.nih.gov/pubmed/29466368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192175
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