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NPPB modulates apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling

When treating glaucoma, excessive scar tissue reactions reduce the postoperative survival rate of the filtering bleb. Accumulating evidence has demonstrated that the proliferation, migration and extracellular matrix (ECM) synthesis of fibroblasts are important molecular mechanisms underlying scar fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Med
Hauptverfasser: Sun, Lixia, Dong, Yaru, Zhao, Jing, Yin, Yuan, Tong, Bainan, Zheng, Yajuan, Xin, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819927/
https://ncbi.nlm.nih.gov/pubmed/29286070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3323
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