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Use of a machine learning-based high content analysis approach to identify photoreceptor neurite promoting molecules

PURPOSE: High content analysis (HCA) has become a leading methodology in phenotypic drug discovery efforts. Typical HCA workflows include imaging cells using an automated microscope and analyzing the data using algorithms designed to quantify one or more specific phenotypes of interest. Due to the r...

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Vydáno v:Adv Exp Med Biol
Hlavní autoři: Fuller, John A., Berlinicke, Cynthia A., Inglese, James, Zack, Donald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815518/
https://ncbi.nlm.nih.gov/pubmed/26427464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17121-0_79
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