Therapeutic Potential of Afatinib for Cancers with ERBB2 (HER2) Transmembrane Domain Mutations G660D and V659E

We previously reported on a family with hereditary lung cancer, in which a germline mutation in the transmembrane domain (G660D) of avian erythroblastic leukemia viral oncogene homolog 2 (erb‐b2 receptor tyrosine kinase 2) (ERBB2; human epidermal growth factor receptor 2 [HER2]) seemed to be respons...

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Vydáno v:Oncologist
Hlavní autoři: Yamamoto, Hiromasa, Toyooka, Shinichi, Ninomiya, Takashi, Matsumoto, Shigemi, Kanai, Masashi, Tomida, Shuta, Kiura, Katsuyuki, Muto, Manabu, Suzawa, Ken, Desmeules, Patrice, Kris, Mark G., Li, Bob T., Ladanyi, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2017
Témata:
Precision Medicine Clinic: Molecular Tumor Board
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813752/
https://ncbi.nlm.nih.gov/pubmed/29146616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0345
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