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Protein Identification in Imaging Mass Spectrometry through Spatially Targeted Liquid Micro-Extractions

RATIONALE: Liquid extraction surface analysis (LESA) can be used to generate spatially-directed protein identifications in an imaging mass spectrometry (IMS) workflow. This approach involves the use of robotic micro-extractions coupled to online liquid chromatography (LC). We have characterized the...

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Detalhes bibliográficos
Publicado no:Rapid Commun Mass Spectrom
Main Authors: Ryan, Daniel J., Nei, David, Prentice, Boone M., Rose, Kristie L., Caprioli, Richard M., Spraggins, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812809/
https://ncbi.nlm.nih.gov/pubmed/29226434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.8042
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