Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments

Pseudomonas aeruginosa causes devastating infections in immunocompromised individuals. Once established, P. aeruginosa infections become incredibly difficult to treat due to the development of antibiotic tolerant, aggregated communities known as biofilms. A hyper-biofilm forming clinical variant of...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Pestrak, Matthew J., Chaney, Sarah B., Eggleston, Heather C., Dellos-Nolan, Sheri, Dixit, Sriteja, Mathew-Steiner, Shomita S., Roy, Sashwati, Parsek, Matthew R., Sen, Chandan K., Wozniak, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812653/
https://ncbi.nlm.nih.gov/pubmed/29394295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006842
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