Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway

The use of serotype 5 adenovirus (Ad)-derived vectors in vaccination is confronted to preexisting anti-Ad immunity. Epitope display on Ad capsid is currently being investigated as an alternative approach of vaccination. The present study seeks to better understand virus- and host-related factors con...

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Detalhes bibliográficos
Publicado no:Front Immunol
Principais autores: Anchim, Aleksandra, Raddi, Najat, Zig, Lena, Perrieau, Patrick, Le Goffic, Ronan, Ryffel, Bernhard, Benihoud, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807684/
https://ncbi.nlm.nih.gov/pubmed/29459860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00124
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