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Mechanisms of Mitotic Kinase Regulation: A Structural Perspective

Protein kinases are major regulators of mitosis, with over 30% of the mitotic proteome phosphorylated on serines, threonines and tyrosines. The human genome encodes for 518 kinases that have a structurally conserved catalytic domain and includes about a dozen of cell division specific ones. Yet each...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Welburn, Julie P. I., Jeyaprakash, A. Arockia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807344/
https://ncbi.nlm.nih.gov/pubmed/29459892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00006
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