Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Concern has been raised over increased male reproductive disorders in the Western world, and the disruption of male endocrinology has been suggested to play a central role. Several studies have shown that mild analgesics exposure during fetal life is associated with antiandrogenic effects and congen...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kristensen, David Møbjerg, Desdoits-Lethimonier, Christèle, Mackey, Abigail L., Dalgaard, Marlene Danner, De Masi, Federico, Munkbøl, Cecilie Hurup, Styrishave, Bjarne, Antignac, Jean-Philippe, Le Bizec, Bruno, Platel, Christian, Hay-Schmidt, Anders, Jensen, Tina Kold, Lesné, Laurianne, Mazaud-Guittot, Séverine, Kristiansen, Karsten, Brunak, Søren, Kjaer, Michael, Juul, Anders, Jégou, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789927/
https://ncbi.nlm.nih.gov/pubmed/29311296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715035115
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