Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes

Whether nucleic acids that circulate in blood have any patho-physiological functions in the host have not been explored. We report here that far from being inert molecules, circulating nucleic acids have significant biological activities of their own that are deleterious to healthy cells of the body...

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Vydáno v:J Biosci
Hlavní autoři: Mittra, Indraneel, Khare, Naveen Kumar, Raghuram, Gorantla Venkata, Chaubal, Rohan, Khambatti, Fatema, Gupta, Deepika, Gaikwad, Ashwini, Prasannan, Preeti, Singh, Akshita, Iyer, Aishwarya, Singh, Ankita, Upadhyay, Pawan, Nair, Naveen Kumar, Mishra, Pradyumna Kumar, Dutt, Amit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779614/
https://ncbi.nlm.nih.gov/pubmed/25740145
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