Microsatellite stability and mismatch repair proficiency in nasopharyngeal carcinoma may not predict programmed death-1 blockade resistance

The US FDA granted accelerated approval to pembrolizumab for microsatellite instability-high and mismatch repair deficient cancers. The response of programmed death-1 blockade in mismatch repair proficiency (pMMR) colorectal cancer is very poor, however, whether such treatment is effective in pMMR n...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Liao, Xiyi, Zhao, Liang, Wu, Sangang, Zheng, Hua, Chen, Haojun, Zhang, Huan, Wang, ZiJing, Lin, Qin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762592/
https://ncbi.nlm.nih.gov/pubmed/29348907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22938
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