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Isomeric Separation of Permethylated Glycans by Porous Graphitic Carbon (PGC)-LC-MS/MS at High-Temperatures

Permethylation is a common derivatization method for MS-based glycomic analyses. Permethylation enhances glycan ionization efficiency in positive MS analysis and improves glycan structural stability. Recent biological glycomic studies have added to the growing body of knowledge and suggest the need...

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Détails bibliographiques
Publié dans:Anal Chem
Auteurs principaux: Zhou, Shiyue, Huang, Yifan, Dong, Xue, Peng, Wenjing, Veillon, Lucas, Kitagawa, Daniel A. S., Aquino, Adelia J. A., Mechref, Yehia
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761069/
https://ncbi.nlm.nih.gov/pubmed/28475308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00747
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