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Isomeric Separation of Permethylated Glycans by Porous Graphitic Carbon (PGC)-LC-MS/MS at High-Temperatures

Permethylation is a common derivatization method for MS-based glycomic analyses. Permethylation enhances glycan ionization efficiency in positive MS analysis and improves glycan structural stability. Recent biological glycomic studies have added to the growing body of knowledge and suggest the need...

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Publicado en:Anal Chem
Autores principales: Zhou, Shiyue, Huang, Yifan, Dong, Xue, Peng, Wenjing, Veillon, Lucas, Kitagawa, Daniel A. S., Aquino, Adelia J. A., Mechref, Yehia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761069/
https://ncbi.nlm.nih.gov/pubmed/28475308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00747
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